Product Overview
Our IsoTis Mozaik™ strip is a compression-resistant, osteoconductive scaffold composed of purified collagen and β-TCP. The matrix readily hydrates with bone marrow aspirate.
Key Features
Clinical Evidence - Equivalent fusion performance to autograft has been demonstrated in a retrospective study on posterolateral lumbar fusion. The study found 100% fusion in all one- and two-level procedures, with an overall fusion rate of 90%.1
Advanced Engineering - With a blend of 20% type 1 bovine collagen and 80% highly purified β-TCP, the matrix was developed to resemble the composition and pore structure of natural human bone. The resorption rate is consistent with the formation of new bone.
Carrier for Cells and Proteins - An interconnected pore structure absorbs bone marrow aspirate, which contains cells and proteins that play an important role in bone formation.
Compression Resistance - A matrix with compression resistance has an increased ability to retain bone marrow aspirate within the matrix.
Radiographic Visualization - The β-TCP component provides radiographic visualization of graft placement.
Terminal Sterilization - As the last step in manufacturing, the scaffold is terminally sterilized.
Indications:
IsoTis Mozaik Strip, combined with Bone Marrow Aspirate (BMA), is intended for use as a bone void filler to fill voids or gaps of the skeletal system in the extremities, spine, and pelvis not intrinsic to the stability of the bony structure. IsoTis Mozaik Strip is also indicated for use in the treatment of surgically treated osseous defects or osseous defects created from traumatic injury to the bone. Following placement in the bony void or gap (defect), IsoTis Mozaik Strip is resorbed and replaced with bone during the healing process. (https://www.seaspine.com)
1 Data on file
